Clinical Research Updates

Latest Medical Research

The latest medical research projects proving the clinical utility of end-tidal CO2 monitoring and the validation of Microstream capnography technology

2011 2010 2009 2008

2011

1) Survey of Alarm Limit Settings for Adult Capnography Users. Spratt G. Society for Technology in Anesthesia 2011.

2) Comparing Capnography Alarm Limits Used in Differing Care Environments. Spratt G. Society for Technology in Anesthesia 2011.

3) Capnography Improves Detection of Respiratory Events During Procedural Sedation: A Meta-Analysis. Waugh JB. Society for Technology in Anesthesia 2011.

4) Pulmonary Index (IPI) Monitoring During Endoscopies in Children. Shaoul R. Society for Technology in Anesthesia 2011.

5) Analysis of the Efficacy of Waveform Capnography Monitoring Using Bag-Valve-Mask Ventilation. Wales, RA. Society for Technology in Anesthesia 2011.

6) End Tidal Carbon Dioxide Levels Predict Cardiac Arrest. Manyam H. Society for Technology in Anesthesia 2011.

7) Influence of Position on Ventilation in the African Black Rhinoceros (Diceros Biconis) Undergoing Anesthesia in the Wild. Radcliffe R et al. Society for Technology in Anesthesia 2011.

8) A Pilot Evaluation of a Novel Screening Tool for Sleep Related Breathing Disorders. Colman M et al. Society for Technology in Anesthesia 2011.

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2010

Respiratory Care

1) Integrated Pulmonary Index as a Possible Screening Tool for Pulmonary Disease. Hill J. Respiratory Care Nov 2010: Volume 55, Number 11, page 1519.

2) Integrated Pulmonary Index Stability in Healthy Adults Under Changing Conditions. Waugh, JB. Respiratory Care Nov 2010: Volume 55, Number 11, page 1522.

3) Effect of Heliox on End-Tidal CO2 and Respiratory Rate Measurement in Healthy Adults. Gardner D. Respiratory Care Nov 2010: Volume 55, Number 11, page 1588

Critical Care/PACU

1) The IPI Identifies the Window of Opportunity for Treatment Before Cardio-Respiratory Arrest. Einav S. Resuscitation, Volume 81, Issue 2, Supplement 1, December 2010, Page S42.

2) Capnography in Premature Infants Ventilated with High Frequency Ventilation: A Pilot Study. Kugelman A, Riskin A, Shoris I, Bader D. PAS - Pediatric Academic Societies. May 2010.

3) End Tidal Carbon Dioxide Predicts Cardiac Arrest. Manyam H, Thiagarajah P, Patel G, French R, Chaluvadi S, Balaan M. American Heart Association Resuscitation Science Symposium

Procedural Sedation & Analgesia

1) Quantitative and Qualitative Assessment of the Oxygen Delivery and EtCO2 sampling During an Upper Endoscopy Procedure with the Oridion Smart Capnoline Guardian. Gozal D, Cohen M, Wengrower D, Dancour A. Gastrointestinal Endoscopy. April 2010.

2) Bariatric Patients Can Be Safely Managed Postoperatively on a Medical Surgical Unit Utilizing Continuous Cardiorespiratory Monitoring. Holmes et al. Surgery for Obesity and Related Diseases. June 2010.

3) Pilot Study of the Smart Capnography Integrated Pulmonary Index^TM in the Gastroenterology Procedure Unit. Heard LA, Jiang H, Fredette ME, Atmadja M, Lightdale JR. 2010; SGNA/DDW.

4) Capnography Is Superior to Pulse Oximetry for the Detection of Respiratory Depression During Colonoscopy. Cacho G et al. Revista Espanola De Enfermedades Digestivas. February 2010; 102(2), 86-89.

5) EtCO2 Monitoring in the Post-Operative Surgical Patient Respiratory Care. Daniels C. Nov 2010: Volume 55, Number 11.

Emergency Medicine

1) Analysis of Abnormal Events Identified by the Integrated Pulmonary Index In Normal Adults During Noninvasive Positive Pressure Ventilation. Waugh JB, Taft AA, Niebel KH. Prehospital Emergency Care (NAEMSP). January 2010; Volume 14, (Suppl 1), 30-31.

2) Analysis of the Efficacy of Waveform Capnography Monitoring Using Bag-Valve-Mask Ventilation. Wales RA, Dyott W. Prehospital Emergency Care (NAEMSP). January 2010; Volume 14, (Suppl 1), 48-49.

3) Partial Pressure of End-tidal Carbon Dioxide – Reliable Criteria for Termination of Non-traumatic Cardiac Arrest Resuscitative Efforts in the Field. Grmec et al. Resuscitation, Volume 81, Issue 2, Supplement 1, December 2010, Page S26.

4) Capnography as a Survival Predictor in Cardiopulmonary Resuscitation.Farinha LF. Resuscitation, Volume 81, Issue 2, Supplement 1, December 2010, Page S57.Sleep and Pulmonary Rehab

5) End-tidal Carbon Dioxide Concentration Monitoring in Obstructive Sleep Apnea Patients. Weihu C, Jingying Y, Demin H, Yuhuan Z, Jiangyong W. American Journal of Otolaryngology. May 2010, 1-4.

Clinical Education

1) Preventing Unnecessary Deaths with Capnography. Spratt G. AARC Times. February 2010; 28-32.

2) Revenue Generation Model Screening for OSA During Hospitalizations Commonly Monitored With Capnography. Boyd P. Journal of Sleep and Sleep Disorders Research.

3) Web Application to Track Patient Safety During Sedation, Epps C. APSF newsletter. Spring 2010; Volume 25, no 1.

4) Capnography Monitoring. Provencher T and Nuccio P. RT August 2010.

5) The Use of NIV on COPD Patients. Murray M. RT Nov 2010.

6) Professional Skills and Competence for Safe and Effective Procedural Sedation in Children: Recommendations Based on a Systemic Review of the Literature. Piet LJ et al. International Journal of Pediatrics; Volume 2010, Volume 2010, Article ID 934298, 16 pages.

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2009

1) A role of end-tidal CO2 monitoring for assessment of tracheal intubations in very low birth weight infants during neonatal resuscitation at birth. Hosono S, et al. Journal of Perinatal Medicine. January 2009; Vol. 37, Issue 1, 79-84. Click here

2) Comparison of Capnography Filter Lines for Nose and Mouth Breathing of End Tidal Carbon Dioxide Sampling With and Without Supplemental Oxygen. Colman Y, David U. STA Annual Meeting Abstracts, January 2009. Click here

3) The Integrated Pulmonary Index: Validity and Application in the Pediatric Population. Gozal D, Gozal Y. STA Annual Meeting Abstracts, January 2009. Click here

4) Reliability of the Integrated Pulmonary Index Postoperatively. Gozal Y, Gozal D. STA Annual Meeting Abstracts, January 2009. Click here

5) Postural changes and end-tidal carbon dioxide in the black rhinoceros (DICEROS BICORNIS) and its importance to field anesthesia. Jago M, Morkel P, et al. STA Annual Meeting Abstracts, January 2009. Click here

6) End Tidal CO2 Measurements with Non-Invasive Ventilation. Nuccio PF, Jackson MR. STA Annual Meeting Abstracts, January 2009. Click here

7) Capnography filter lines adapted for pressure (PTAF) to detect apnea and hypopnea as a possible method for sleep disorder breathing pattern recognition. Whitesell PL, Rousseau DA, Wales RA. STA Annual Meeting Abstracts, January 2009. Click here

8) The correlation and level of agreement between end-tidal and blood gas pCO2 in children with respiratory distress: a retrospective analysis. Moses JM, Alexander JL, Agus MSD. BMC Pediatrics. March 2009; Vol. 9(20). Click here

9) Efficient ventilation utilizing noninvasive capnography. Waugh JB, Epps CA. AARC Times. March 2009.

10) Quality assurance report on the use of continuous positive airway pressure and end-tidal carbon dioxide during respiratory distress in field emergency care. Lain D, Bourn S. Critical Care. March 2009; Vol. 13, Suppl. 1. Click here

11) Universal capnography: A vital asset that can improve patient care on almost any call. Brandt P. A supplement to JEMS sponsored by Physio-Control. March 2009; 14-17. Click here

12) Continuous monitoring of carbon dioxide reactivity in traumatic brain injury. De La Cerda G, Verma V. Critical Care, March 2009; Vol. 13, Suppl. 1. Click here

13) La capnografia en los servicios de emergencia medica. Diez-Picazo LD, et al. Semergen, March 2009; Vol. 35, Issue 3, 138-143.

14) Sedation Medication received and adverse events related to sedation for brain MRI in children with an without developmental disabilities. Kannikeswaran N, et al. Pediatric Anesthesia, March 2009; Vol. 19, Issue 3, 250-256. Click here

15) Implementing Capnography For Procedural Sedation: Strengthening Your Safety Net. Martini T. Gastroenterology Nursing, March/April 2009; Vol. 32(2),146.

16) Assessment of end tidal carbon dioxide during pediatric and adult sedation for endoscopic procedures. Yarchi D, et al. Gastrointestinal Endoscopy. April 2009; Vol. 69, Issue 4, 877-882. Click here

17) Capnographic Monitoring of Respiratory Activity Improves Safety of Sedation for Endoscopic Cholangiopancreatography and Ultrasonography. Qadeer MA, Vargo JJ, et al. Gastroenterology, May 2009. Click here

18) Correlation of Microstream End Tidal Carbon Dioxide with Blood Gas Measurements in Ventilated Neonates. Singh B, et al. Society of Pediatric Research (SPR), May 2009.

19) Does Obesity or Signs of Obstructive Sleep Apnea Predict Adverse Events during Procedural Sedation and Analgesia? Slater AC, et al. Society of Pediatric Research (SPR), May 2009.

20) Utility of End Tidal Carbon Dioxide Monitoring in Detection of Acute Respiratory Events during Sedation for Brain MRI in Children with Developmental Disabilities. Kannikeswaran N, et al. Society of Pediatric Research (SPR), May 2009.

21) Respiratory Depression in Intoxicated Adolescents and Young Adults. Langhan ML. Society of Pediatric Research (SPR), May 2009.

22) Capnographic Monitoring in Respiratory Emergencies. Nagler J, Krauss B. Clinical Pediatric Emergency Medicine, June 2009. Click here

23) Validation of the Integrated Pulmonary Index in The Post Anesthesia Care Unit. Gozal Y, Gozal D. European Journal of Anaesthesiology. June 2009; Vol. 26, Suppl. 45, 36.

24) Capnography during CPR in SUMMA 112: Preliminary Study. Diez-Picazo LD, et al. Congreso Nacional SEMES 2009. June 2009.

25) Bedside End Tidal CO2 As A Screening Tool To Exclude Pulmonary Embolism. Hemnes A, et al. European Respiratory Journal Express. August 2009.

26) Does end tidal CO2 monitoring during emergency department procedural sedation and analgesia with propofol decrease the incidence of hypoxic events? A randomized, controlled trial. Deitch K, Miner J, et al. Annals of Emergency Medicine. September 2009. Click here

27) Detection of carbon dioxide thresholds using low-flow sidestream capnography in ventilated preterm infants. Lopez E, Grabar S, Barbier A, Krauss B, et al. Intensive Care Medicine. November 2009; Vol 35, No 11; 1942-1949. Click here

28) Algorithm Simplifies Ventilation Information. Heller A. Anesthesiology News. September 2009; Vol. 35, Issue 9.

29) The Integrated Pulmonary Index: Validity, Safety and Application in the Pediatric Population. Gozal D, Gozal Y. American Society of Anesthesiologists. October 2009. Click here

30) Case Record Form Entry Time for Safesedation.Org. Epps C, Waugh J, Weiser R. American Society of Anesthesiologists. October 2009

31) Return-on-Investment (ROI) Analysis of Capnography Monitoring in Post- Operative Care. Boyd P. American Society of Anesthesiologists. October 2009.

32) Influence of sampling site on end tidal carbon dioxide levels (PetCO2) during non-invasive positive pressure ventilation (NPPV). Taft A, Waugh J, Pippin G. 2009 Open Forum Abstracts, Respiratory Care, December 2009. Click here

33) Comparison of capnography derived respiratory rate alarm frequency using the SARA algorithm versus an established non-adaptive respiratory rate alarm management algorithm in bariatric surgical patients. Hockman S, Glembot T, Niebel K. 2009 Open Forum Abstracts, Respiratory Care, December 2009. Click here

34) Position statement: nonanesthesiologist administration of propofol for GI endoscopy. Gastrointestinal Endoscopy, 2009; Vol. 70, No. 6, 1053-1059. Click here

35) Integrated Pulmonary Index™ (IPI), Wikipedia http://en.wikipedia.org/wiki/Integrated_Pulmonary_Index

36) Use of microstream capnography and alveolar recruitment during off-pump coronary artery bypass grafting. Suborov EV, Postnikova EA, et al. Anesthesiology and Intensive Care, 2009. No. 4. Click here

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2008

1) Capnograph Analysis Detects Obstructed Breathing and Improves Alarm Specificity During Patient Controlled Analgesia Monitoring. Overdyk F, et al. Anesthesiology, 2008. Click here

2) Does Medical Education and Training Influence Patient Safety? Fitch-Bergenholtz K, Cummings A, Lain D. Anesthesiology, 2008. Click here

3) A Novel Integrated Pulmonary Index (IPI) Quantifies Heart Rate, EtCO2, Respiratory Rate and Spo2. Taft A, et al. Anesthesiology, 2008. Click here

4) Capnography in Upper Gastrointestinal Endoscopy with the Oridion BiteBloc. Carr-Locke DL, Walsh S. Anesthesiology, 2008. Click here

5) Continuous, non-invasive arterial CO2 estimation in spontaneously breathing patients after craniotomy. Wolter J, Dimache L, et al. European Journal of Anaesthesiology. 2008; Vol. 25 (Suppl. 44).

6) Capnography and Respiratory Depression. Hutchison R, Rodriguez L. American Journal of Nursing. February 2008; Vol. 108, No. 2, 35-39. Click here

7) Smart Alarm Respiratory Analysis (SARA) used in capnography to reduce alarms during spontaneous breathing. Colman J, Cohen J, Lain D. Anesthesia & Analgesia (Suppl.), April 2008; Vol. 106, No. 4S.

8) Monitoring to Improve Ventilation Safety During Sedation and Analgesia. Waugh JB, Khodneva Y, Epps CA, Anesthesia & Analgesia (Suppl.), April 2008; Vol. 106, No. 4S. Click here

9) A Comparison Of Capnographic Waveform Indices And Peak Flow Meter In The Monitoring Of Asthmatic Patients In Emergency Departments. Ab-Rahman NH, Howe TA. Annals of Emergency Medicine. April 2008; Vol. 51, Issue 4, 476-477.

10) A Randomized Controlled Trial on Procedural Sedation Among Adult Patients in Emergency Departments: Comparing Fentanyl With Midazolam Versus Fentanyl With Propofol. Ab-Rahman NH, Hashim A. Annals of Emergency Medicine. April 2008; Vol. 51, Issue 4, 479-480.

11) Expiratory Capnogram Assessing Bronchospasm Versus Expiratory Peak Flow. Hysham Sr H, Claude Sr BJ, Bruno Sr C. Annals of Emergency Medicine. April 2008; Vol. 51, Issue 4, 534.

12) A Study On The Use Of Nasal Capnometry In Patients Presented With Acute Breathlessness In The Emergency Department. Ab-Rahman NH, Mamat AF, Ahmad R, Noh AY, Jaalam K. Annals of Emergency Medicine. April 2008; Vol. 51, Issue 4, 534-535.

13) Nasal Capnography Monitoring: Making Sedation Safer in the Emergency Department. McNaughton G., Stewart G. Annals of Emergency Medicine. April 2008; Vol. 51, Issue 4, 548-549.

14) Capnography Prevents Hypoxemia During ERCP and EUS: A Randomized Controlled Trial. Qadeer M, Vargo J, et al. Gastrointestinal Endoscopy. April 2008; Vol. 67, Issue 5, AB84.

15) Current Utilization of Continuous End-Tidal Carbon Dioxide Monitoring in Pediatric Emergency Departments. Langhan ML, Chen L. Pediatric Emergency Care. April 2008; Vol. 24, No. 4, 211-213. Click here

16) Capnography versus impedance: In search of an optimal strategy for ventilation detection during cardiopulmonary resuscitation. Edelson D, Eilevst J. European Resuscitation Council. May 2008; Vol. 77 (Suppl.), S3.

17) Computerized Continuous Capnography for Prediction of Survival from Resuscitation. Einav S, Matot I. Resuscitation, May 2008; Vol.77 (Suppl.), S34.

18) Quantitative End-Tidal Carbon Dioxide in Acute Exacerbations of Asthma. Langhan ML, Zonfrillo MR, Spiro DM. The Journal of Pediatrics. June 2008; Vol. 152, Issue 6, 829-832. Click here

19) Capnography Monitoring Enhances Safety of Postoperative Patient-Controlled Analgesia. McCarter T, Shaik Z, Scarfo K, Thompson LJ. American Health & Drug Benefits. June 2008; Vol. 1, No. 5, 28-35. Click here

20) The Utility Of Supplemental Oxygen During Emergency Department Procedural Sedation With Propofol: A Randomized, Controlled Trial. Deitch K, Chudnofsky CR, Dominici P. Annals of Emergency Medicine. July 2008; Vol. 52, Issue 1, 1-8. Click here

21) Supplemental Oxygen During Propofol Sedation: Yes or No? Green SM, Krauss B. Annals of Emergency Medicine. July 2008; Vol. 52, Issue 1, 9-10.

22) Patient-Focused Sedation and Analgesia. Lain D. CHEST. August 2008; Vol. 134, No. 2, 468-469. Click here

23) Barriers to Propofol Use in Emergency Medicine. Green SM, Krauss B. Annals of Emergency Medicine. October 2008; Vol. 52, Issue 4, 392-398. Click here

24) End-Tidal Carbon Dioxide (ETCO2) Trending: How Does This Impact the Number of ETCO2 Measurements Recorded on EMS Run Reports? Zuver C, Ralls G, Silvestri S. European Journal of Emergency Medicine. October 2008; Vol. 15, Issue 5.

25) Advances in the Use of Capnography for Nonintubated Patients. B. Krauss. Israeli Journal of Emergency Medicine; November 2008 Vol. 8, No.3, 3-15 Click here

26) Effect of Mask Type, Oxygen Concentration, and Flow Rate on both Exhaled CO2 and Respiratory Frequency Measurement by Capnograph. Nuccio PF, et al., Respiratory Care. November 2008; Vol. 53, No. 11. Click here

27) Assessment of End Tidal CO2 During Pediatric And Adult Sedation For Endoscopic Procedures. Yarchi D, Cohen A, Shaul R. Respiratory Care. November 2008; Vol. 53, No. 11. Click here

28) Effect of Open Versus Closed-Mouth Breathing On Capnography Using Combination Nasal-Oral Sampling Line. Nuccio PF, Niebel KH, Waugh JB. Respiratory Care. November 2008; Vol. 53, No. 11. Click here

29) A Novel Method of Distal End-Tidal CO2 Capnography in Intubated Infants; Comparison With Arterial CO2 and With Proximal Mainstream End-Tidal CO2. Kugelman A, et al. Pediatrics. December 2008; Vol. 122, No. 6, e1219-e1224. Click Here

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